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Personal Responsibility Education Program Innovative Strategies (PREIS)

Cooperative Agreements to USA Nonprofits, For-Profits, Agencies,
and IHEs for Programs Mitigating Teen Pregnancies

Agency Type:


Funding Source:

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U.S. Department of Health and Human Services (HHS) - Administration for Children and Families (ACF) - Administration on Children, Youth and Families (ACYF) - Family and Youth Services Bureau (FYSB)

Deadline Date:

07/26/21 11:59 PM ET Online Submission; or 4:30 PM ET Hard Copy Receipt with Pre-Approval


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Cooperative agreements to USA nonprofit and for-profit organizations, state and local agencies, LEAs, IHEs, and tribal governments and organizations for programs to reduce the rates of teen pregnancies and STIs. Applicants are advised that required registrations may take several weeks to complete. Funded programs should target high-risk and underrepresented youth populations.

PREIS programs address disparities in teen births and rising STI rates through the implementation and evaluation of innovative strategies that are designed to change sexual risk behaviors such as delaying sexual activity, increasing condom or contraceptive use, and reducing pregnancy. Although there is a growing body of research on teen pregnancy among general youth populations, gaps in both research and the availability of interventions related to various high risk and vulnerable youth populations remain. The purpose of the PREIS program is to build the evidence base for adolescent pregnancy prevention interventions that are effective with high risk and vulnerable youth populations and fill gaps with new promising program models.

Under the PREIS program, the following requirements must be addressed:

  1. Innovative strategies
  2. Abstinence and contraception
  3. Adulthood Preparation Subjects (APS)
  4. Medically accurate information
  5. Age appropriate information
  6. Culturally appropriate information
  7. Trauma-informed care
  8. Referrals to healthcare and other services

Interventions must target youth at high risk for pregnancy and address relevant risk and protective factors associated with sexual risk behaviors. Innovative strategies are broadly defined but may include those that:

  • Have technology and/or computer-based components (i.e., apps, web-based learning, gaming)
  • Are implemented in non-traditional settings (e.g., runaway and homeless youth shelters, foster care group homes, juvenile detention centers, faith-based settings)
  • Target hard to reach populations (e.g., runaway and homeless youth, foster care youth, pregnant and parenting youth, victims of human trafficking)
  • Use systems-level approaches (i.e., approaches that aim to affect not only the individual but also multiple levels such as family, community, and institution)

PREIS Program Timeline:

GrantWatch ID#:

GrantWatch ID#: 171722

Estimated Total Program Funding:


Number of Grants:


Estimated Size of Grant:

Award Ceiling: $900,000 Per Budget Period
Award Floor: $600,000 Per Budget Period
Average Projected Award Amount: $750,000 Per Budget Period

Term of Contract:

Anticipated Project Start Date: 09/30/2021

Length of Project Period: 60-month project with five 12-month budget periods.


  • City or township governments
  • County governments
  • For profit organizations other than small businesses
  • Independent school districts
  • Indian housing authorities
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities
  • See RFP and/or Grant Guidelines for full eligibility
  • Small businesses
  • Special district governments
  • State governments

Additional Eligibility Criteria:

The following types of organization are eligible to apply:
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Local and regional school districts
- Public and state-controlled institutions of higher education
- Native American tribal governments (federally recognized)
- Public housing authorities/Indian housing authorities
- Nonprofits having 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits without 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For-profit organizations other than small businesses
- Local affiliates of national organizations
- Small businesses

Applications from collaboratives and/or consortiums must identify a primary applicant responsible for administering the grant. A primary applicant must be named in the application, and the application must include an MOU for each partnering organization.

ACYF/FYSB strongly encourages applications from Indian tribes, tribal organizations, and tribal entities, including Indian schools, tribal colleges and universities, and entities that target services to marginalized youth populations.

Faith-based organizations may apply for this award on the same basis as any other organization, as set forth at and, subject to the protections and requirements of this part and 42 U.S.C. 2000bb et seq., the Department will not, in the selection of recipients, discriminate against an organization on the basis of the organization’s religious character, affiliation, or exercise.

Applications from individuals (including sole proprietorships) and foreign entities are not eligible and will be disqualified from competitive review and from funding under this announcement.

Funding Restrictions:

Pre-Application Information:

The deadline for electronic application submission is 11:59 p.m., ET on July 26, 2021.

The deadline for receipt of paper applications for applicants that have been approved for an exemption from electronic submission is 4:30 p.m., ET on July 26, 2021.

ACF requires electronic submission of applications at Paper applications received from applicants that have not been approved for an exemption from required electronic submission will be disqualified from competitive review and from funding under this announcement.

The registration process can take up to four weeks to complete. Therefore, registration should be done in sufficient time to ensure it does not impact your ability to meet required application submission deadlines.

All entities applying for funding, including renewal funding, must have a Data Universal Numbering System (DUNS) number from Dun & Bradstreet (D&B). In addition to having a DUNS number, organizations applying online through must register with the System for Award Management (SAM).

View the announcement online:

View this opportunity on

For a list of relevant application documents, go to the Package tab (press Preview) on the link above.

Contact Information:

Before starting your grant application, please review the funding source's website listed below for updates/changes/addendums/conferences/LOIs.

Submission By Mail or HandDeivary with pre-approval:

FYSB Operations Center
c/o F2-Solutions
1401 Mercantile Lane
Suite 410
Largo, MD 20774

Program Office Contact:

Jessica Johnson
Administration for Children and Families
Administration on Children, Youth, and Families (ACYF)
Family and Youth Services Bureau (FYSB)
Mary E. Switzer Building
330 C Street, SW
Washington, DC 20201
Phone: (202) 260-6627

Office of Grants Management Contact:

Bridget Shea Westfall
Administration for Children and Families
Office of Grants Management
330 C Street, SW.
Washington, DC 20201
Phone: (202) 401-5542

CFDA Number:


Funding or Pin Number:


URL for Full Text (RFP):

Geographic Focus:

USA: Alabama;   Alaska;   Arizona;   Arkansas;   California;   Colorado;   Connecticut;   Delaware;   Florida;   Georgia;   Hawaii;   Idaho;   Illinois;   Indiana;   Iowa;   Kansas;   Kentucky;   Louisiana;   Maine;   Maryland;   Massachusetts;   Michigan;   Minnesota;   Mississippi;   Missouri;   Montana;   Nebraska;   Nevada;   New Hampshire;   New Jersey;   New Mexico;   New York City;   New York;   North Carolina;   North Dakota;   Ohio;   Oklahoma;   Oregon;   Pennsylvania;   Rhode Island;   South Carolina;   South Dakota;   Tennessee;   Texas;   Utah;   Vermont;   Virginia;   Washington, DC;   Washington;   West Virginia;   Wisconsin;   Wyoming

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