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2020 Innovation Grant

Grants to USA and Canada Researchers for New and Creative
Approaches to Pediatric Cancer Treatment and Cures

Agency Type:

Foundation / Corporation

Funding Source:

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Alex's Lemonade Stand Foundation (ALSF)

LOI Date:


Deadline Date:

04/06/20 11:59 PM ET


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Grants to USA and Canada academic faculty for new, creative approaches to pediatric oncology research. A letter of intent is required prior to submitting a full application. Funding is intended for research projects with promising and novel approaches to finding causes and cures for childhood cancers.

Innovation Grants are designed to provide critical and significant seed funding for experienced investigators. Proposals should have clinical translation in view. This may represent a change in research direction and/or an innovative new idea that moves away from an investigator’s prior research but for which a strong case is made for the potential impact on childhood cancers. 

Evaluation Criteria:

  • Proposal must be hypothesis-driven and mechanistic.
  • Innovation must be clearly presented.
  • Potential for major scientific impact in pediatric oncology is critical.
  • While preliminary data are not required, the applicant must demonstrate feasibility of the research plan.
  • Resource sharing is an expected outcome of a completed project. The review will consider how outputs are shared as a component of impact.

GrantWatch ID#:

GrantWatch ID#: 184362

Estimated Size of Grant:

The grant is up to $125,000 per year.

Term of Contract:

The grant is for two years. A no-cost extension is permitted if progress is demonstrated and budget properly justified.
- Project Start Date: October 1, 2020
- Project End Date: September 30, 2022

Additional Eligibility Criteria:

Innovation Grants will support research proposals to be carried out by investigators who are already established, have a recent track record of peer-reviewed publications and evidence of successfully competing for extramural funding.

Applicant Eligibility Criteria
- Applicants must have a faculty appointment at an academic institution.
- Applicant may be M.D., D.O., Ph.D, or M.D./Ph.D.
- Track record of publication and funding productivity in the last 5 years must demonstrate that the project can be accomplished by the investigator(s).

- Grants must be focused on pediatric translational oncology, from understanding basic biologic underpinnings to new therapies.
- ALSF does not accept proposals for research utilizing human embryonic stem cells or non-human primates. (Research with human induced pluripotent stem cells is permissible.)
- While an Investigator may submit more than one LOI, and in the event that more than one LOI were approved, only one full application per Investigator may be submitted.
- One resubmission of a previously ALSF reviewed application is permitted.
- ALSF will only consider letters of intent from U.S. or Canadian institutions. However, the PI need not be a U.S. citizen.
- Institutions must have non-profit tax status.

Pre-Application Information:

Important Dates:
- LOI Due Date: November 4, 2019 (11:59 pm Eastern Time)
- Invitation to Submit Full Application: February 2020
- Full Application Due Date: April 5, 2020
- Award Notification: July 2020
- Project Start Date: October 1, 2020
- Project End Date: September 30, 2022
- Progress Report: September 13, 2021 (with financials ending 8/31/21)
- Final Report: November 1, 2022 (with financials ending 9/30/22)

Applications must be submitted through ALSF’s online portal.


Contact Information:

Before starting your grant application, please review the funding source's website listed below for updates/changes/addendums/conferences/LOIs.

Register and apply:

Alex’s Lemonade Stand Foundation for Childhood Cancer
111 Presidential Blvd., Suite 203
Bala Cynwyd, PA 19004

Phone: 866.333.1213
Fax: 610.649.3038

All questions can be submitted to:

URL for Full Text (RFP):

Geographic Focus:

USA: Alabama;   Alaska;   Arizona;   Arkansas;   California;   Colorado;   Connecticut;   Delaware;   Florida;   Georgia;   Hawaii;   Idaho;   Illinois;   Indiana;   Iowa;   Kansas;   Kentucky;   Louisiana;   Maine;   Maryland;   Massachusetts;   Michigan;   Minnesota;   Mississippi;   Missouri;   Montana;   Nebraska;   Nevada;   New Hampshire;   New Jersey;   New Mexico;   New York City;   New York;   North Carolina;   North Dakota;   Ohio;   Oklahoma;   Oregon;   Pennsylvania;   Rhode Island;   South Carolina;   South Dakota;   Tennessee;   Texas;   Utah;   Vermont;   Virginia;   Washington, DC;   Washington;   West Virginia;   Wisconsin;   Wyoming

Canada: Alberta   British Columbia   Manitoba   New Brunswick   Newfoundland and Labrador   Northwest Territories   Nova Scotia   Nunavut   Ontario   Prince Edward Island   Quebec   Saskatchewan   Yukon

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