326 South Dakota Small Business Grants

326 Small Business Grants for South Dakota

Discover grants available to businesses, including for-profit companies, corporations, and small businesses. Funding supports innovation, development, operational upgrades, sustainability initiatives, and business expansion efforts.

See foundations that have given grants for Small Business

Grants to USA and Canada Researchers at IHEs and For-Profits for Research on the Safety of Ath...

Deadline: 10/31/25

Grants of up to $50,000 to USA and Canada researchers at IHEs and for-profit organizations to conduct research on the safety of athletic equipment. Funding is intended for research projects of limited scope that will improve the safety of athletes through improved equi...

GrantWatch ID#: 214887

Grants to USA Investigators at Nonprofits, For-Profits, and IHEs for Scientific Research Proje...

Deadline: 11/12/25

Grants to USA investigators affiliated with nonprofit organizations, for-profits, and IHEs for scientific research projects related to neuroscience. Eligible proposals focus on either innovative research projects or projects to advance data sharing in the field. Fundin...

GrantWatch ID#: 212262

Grants to USA, Canada, and International Researchers for Studies Related to Dementia and Alzhe...

Deadline: 11/17/25 LOI Date: 09/15/25

Grants to USA, Canada, and International clinicians and researchers at universities, medical centers, nonprofit organizations, and biotech companies for studies related to dementia and Alzheimer's disease. Applicants must submit a letter of intent prior to submitting a...

GrantWatch ID#: 181960

Grants to USA, Canada, and International Researchers for Studies Related to Alzheimer's Diseas...

Deadline: 11/17/25 LOI Date: 09/15/25

Grants to USA, Canada, and International clinicians and researchers working at universities, academic medical centers, nonprofits, and biotechnology companies for research related to Alzheimer's Disease interventions. Applicants must submit an LOI prior to submitting a...

GrantWatch ID#: 182777

Grants to USA, Canada, and International Researchers and Clinicians for Research Related to De...

Deadline: 11/17/25 LOI Date: 09/15/25

Grants to USA, Canada, and International clinicians and researchers based at nonprofit and for-profit organizations, IHEs, and medical centers for Alzheimer's disease treatment research. Applicants must submit a letter of intent prior to applying. Funding is intended t...

GrantWatch ID#: 187795

Grants to USA, Canada, and International Nonprofits, Industries, Research Organizations, and A...

Deadline: 12/12/25 Conference Date: 06/26/25 LOI Date: 09/17/25

Grants to USA, Canada, and International nonprofit organizations, industries, research organizations, and academic institutions for projects and research addressing occupational health and safety. Applicants must submit a letter of intent prior to applying. Application...

GrantWatch ID#: 221239

Grants to South Dakota Healthcare Entities to Boost Employment in Selected Communities

Deadline: 12/31/25

Grants of $10,000 per employee to South Dakota healthcare facilities to recruit healthcare workers for small, remote communities. Preference will be given to programs that employ recent graduates. To be eligible, healthcare professionals must be newly employed by a fac...

GrantWatch ID#: 165706

Grants and In-Kind Support to USA Small Businesses for Business Advancement Activities

Deadline: 12/31/25

Grants of $5,000 and in-kind support to USA small business owners to advance their businesses. In addition to funding, recipients will have access to coaching sessions, accounting tools, and banking perks. Eligible businesses provide a service, address a community need...

GrantWatch ID#: 210758
Upcoming

Grants to USA Nonprofits and For-Profits for Conferences on Patient-Centered Health Research

Deadline: 01/12/26 LOI Date: 09/29/25

Grants to USA nonprofit and for-profit organizations for conferences and meetings related to improving health outcomes through patient-centered care. Applicants must submit a letter of intent prior to submitting a full application. The program encourages, but does not ...

GrantWatch ID#: 178599
Upcoming

Grants to USA Nonprofits and For-Profits to Improve Research Capacity and Healthcare Outcomes

Deadline: 01/12/26 LOI Date: 09/29/25

Grants to USA nonprofit and for-profit organizations to promote healthcare outcomes and clinical effectiveness research. Applicants must submit a letter of intent and complete required registrations prior to submitting a full application. Funding is intended to support...

GrantWatch ID#: 180287
Upcoming

Grants to USA Nonprofits and For-Profits for Projects to Improve Healthcare Decisions

Deadline: 01/12/26 LOI Date: 09/29/25

Grants to USA nonprofit and for-profit organizations for research support projects that lead to improved healthcare decisions. Applicants must submit a letter of intent and complete required registrations prior to submitting a full application. Funding is intended to s...

GrantWatch ID#: 183094
Upcoming

Contracts for Services to USA Nonprofits, For-Profits, IHEs, and Agencies for Health-Related R...

Deadline: 01/13/26 Conference Date: 08/18/25 LOI Date: 09/23/25

Contracts for services to USA nonprofit and for-profit organizations, IHEs, and government agencies for research projects on a wide range of health-related topics. Applicants must submit a letter of intent prior to submitting a full application. Special emphasis is pla...

GrantWatch ID#: 201364
Upcoming

Contracts for Services to USA Nonprofits and For-Profits to Implement Health-Based Research Co...

Deadline: 01/13/26 LOI Date: 09/23/25

Contracts for services to USA nonprofit and for-profit organizations to implement research findings and promote better-informed health decisions. Applicants must submit an LOI prior to applying. Funding is intended for projects that incorporate active, multi-component ...

GrantWatch ID#: 203173
Upcoming

Grants to USA Research Entities, Agencies, IHEs, Nonprofits, and For-Profits for Large-Scale R...

Deadline: 01/13/26 Conference Date: 08/20/25 LOI Date: 09/23/25

Grants to USA research entities, including agencies, IHEs, and nonprofit and for-profit organizations for large-scale medical research related to the effectiveness of new interventions. Applicants must submit a letter of intent prior to submitting a full application. F...

GrantWatch ID#: 205679
Upcoming

Contracts for Services to USA Nonprofits, For-Profits, Agencies, and IHEs for Research to Unde...

Deadline: 01/13/26 Conference Date: 08/22/25 LOI Date: 09/23/25

Contracts for services to USA nonprofit and for-profit organizations, agencies, and IHEs for research projects to understand patient engagement in medical research. Applicants must submit an LOI prior to submitting a full application. Funding is intended for research t...

GrantWatch ID#: 207669
Upcoming

Grants to USA Agencies, Nonprofits, For-Profits, and IHEs for Research Related to Improving Cl...

Deadline: 01/13/26 LOI Date: 09/23/25

Grants to USA government agencies, nonprofit and for-profit research organizations, and institutions of higher education for research projects related to improving clinical effectiveness research (CER). Applicants must submit a letter of intent prior to applying. The p...

GrantWatch ID#: 212662
Upcoming

Grants to USA Research Entities, Agencies, IHEs, Nonprofits, and For-Profits for Research on t...

Deadline: 01/13/26 Conference Date: 08/19/25 LOI Date: 09/23/25

Grants to USA research entities, including agencies, IHEs, and nonprofit and for-profit organizations, for research projects addressing the efficacy of rare disease treatment programs. Applicants must submit an LOI prior to applying. Funding is intended for projects re...

GrantWatch ID#: 214407

Grants to USA Nonprofits, For-Profits, IHEs, and Agencies to Strengthen the Quality of STEM Ed...

Deadline: 01/14/26

Grants to USA nonprofit and for-profit organizations, IHEs, and government agencies to strengthen the quality of STEM education for the general public. Applicants are advised that required registrations may take several weeks to complete. Funding is intended for a broa...

GrantWatch ID#: 154919

Grants and Cooperative Agreements to USA Nonprofits, For-Profits, and IHEs for Research Relate...

Deadline: 01/15/26

Grants and cooperative agreements to USA and territories nonprofit and for-profit organizations and institutions of higher education for research related to Cyber Infrastructure. Applicants are advised that the required registrations must be completed prior to applying...

GrantWatch ID#: 201819

Grants to USA, Canada, and International Nonprofits for Research and Public Engagement Projects

Deadline: 01/16/26 LOI Date: 08/15/25

Grants to USA, Canada, and International nonprofit organizations for research projects and public engagement programs that address a wide range of issues, including but not limited to, entrepreneurship, science, society, and religion. Applicants must submit an online f...

GrantWatch ID#: 171288

Grants to USA Nonprofits, For-Profits, IHEs, Agencies, Tribes, and Faith-Based Organizations t...

Deadline: 01/27/26

Grants to USA and territories nonprofit and for-profit organizations, IHEs, government agencies, tribal organizations, and faith-based organizations to improve methods of educating researchers who focus on biomedical, clinical, and behavioral studies. Applicants are ad...

GrantWatch ID#: 212199

Grants to USA Nonprofits, IHEs, and For-Profits to Promote Scientific Research Careers

Deadline: 01/28/26 LOI Date: 12/29/25

Grants to USA nonprofit organizations, IHEs, and for-profit organizations to expand the workforce in the area of scientific research. Applicants are advised that required registrations may take six weeks or more. Funding is intended to support educational activities th...

GrantWatch ID#: 195215

Grants to USA Small Specialty Crop Businesses to Offset Expenses Related to Safety Regulations...

Deadline: 01/31/26

Grants to USA and territories small specialty crop businesses to offset expenses related to safety regulations and requirements. Funding is intended for on-farm food safety program expenses, including certification receipt or renewal, as well as related costs. Applican...

GrantWatch ID#: 204140

Grants to USA, Canada, and International Investigators for Innovative Research on Inflammatory...

Deadline: 02/02/26 LOI Date: 09/30/25

Grants to USA, Canada, and International investigators affiliated with nonprofit and for-profit research institutions, medical centers, and universities to support innovative research on inflammatory bowel disease. Applicants are required to submit an LOI prior to subm...

GrantWatch ID#: 182892

Cooperative Agreements to USA Agencies, Nonprofits, For-Profits, and IHEs for the Production a...

Deadline: 02/02/26 LOI Date: 01/03/26

Cooperative agreements to USA and territories agencies, nonprofit and for-profit organizations, and IHEs to support the production and distribution of specific reagents at eligible facilities. Applicants are advised that required registrations may take several weeks to...

GrantWatch ID#: 217253
Upcoming

Grants to USA Nonprofits, IHEs, Museums, Research Laboratories, and Tribes for PreK-12 Compute...

Deadline: 02/11/26

Grants to USA nonprofits, IHEs, museums, research laboratories, professional societies, and Tribes to promote computer science and computational thinking educational opportunities for PreK-12 students. Funding is intended to support researcher-practitioner collaboratio...

GrantWatch ID#: 183161

Grants to USA IHEs, Nonprofits, For-Profits, and Agencies to Support Early-Career Researchers ...

Deadline: 02/27/26 LOI Date: 01/28/26

Grants to USA and territories IHEs, nonprofit and for-profit organizations, and agencies to support early-career researchers studying specific topics. Applicants are advised that required registrations may take several weeks to complete. Funding is intended to support ...

GrantWatch ID#: 218296

Grants to USA IHEs, Nonprofits, Businesses, and Tribes for Research Projects to Improve Infras...

Deadline: 03/06/26

Grants to USA IHEs, nonprofit organizations, businesses, and tribes for research projects to improve infrastructure throughout the country. Applicants are advised that required registrations may take several weeks to finalize. Funding is intended to support projects wi...

GrantWatch ID#: 212589

Grants for AIDS and HIV Related Research to USA, Canada, and International Nonprofits, For-Pro...

Deadline: 03/13/26 LOI Date: 02/11/26

Grants to USA, Canada, and International nonprofit and for-profit organizations, IHEs, and agencies for research related to AIDS and HIV. Applicants are advised that required registrations may take several weeks to complete. Funding is intended to support multi-compone...

GrantWatch ID#: 192422

Grants to USA Nonprofits, For-Profits, IHEs, and Agencies to Provide Research Experiences to S...

Deadline: 03/17/26 LOI Date: 02/17/26

Grants to USA and territories nonprofit and for-profit organizations, IHEs, and agencies to provide research experiences to students. Applicants are advised that required registrations may take several weeks to complete. Funding is intended to encourage people to enter...

GrantWatch ID#: 215142

Prizes to USA Individuals, Teams, and Private Entities for Models of Effective Translational S...

Deadline: 04/30/26

Prizes of $10,000 to USA individuals, teams, and private entities for models of effective translational science education and training. This challenge is intended to identify particularly effective and innovative teaching approaches and disseminate them in order to cre...

GrantWatch ID#: 217422

Grants and In-Kind Support to USA Early-Stage Jewelry Designers for Activities to Promote Busi...

Deadline: 05/01/26

Grants and in-kind support to USA early-stage jewelry designers for career-building activities. In addition to the cash grant, merchandise, feedback, and industry recognition will be given to emerging entrepreneurs who work primarily in silver. The purpose of the progr...

GrantWatch ID#: 188787

Cooperative Agreements to USA Nonprofits, Agencies, Tribes, IHEs, and For-Profits for Translat...

Deadline: 09/28/26 LOI Date: 07/30/26

Cooperative agreements to USA nonprofit organizations, government agencies, tribes, IHEs, and for-profits for translational and clinical brain research. Applicants are advised that the required registrations must be completed prior to applying. Funding is intended to s...

GrantWatch ID#: 217734

Cooperative Agreements to USA Agencies, For-Profits, IHEs, Tribes, and Nonprofits for Brain Re...

Deadline: 09/28/26 LOI Date: 07/30/26

Cooperative agreements to USA government agencies, for-profits, IHEs, tribes, and nonprofit organizations for brain research. Applicants are advised that the required registrations must be completed prior to applying. Funding is intended for clinical studies for device...

GrantWatch ID#: 217735

Grants to USA and International Nonprofits, Agencies, and For-Profits to Benefit Families, Chi...

Deadline: Ongoing

Grants to USA and International nonprofit organizations, for-profit entities, and agencies for initiatives to benefit families, children, and communities. Applicants are required to submit an LOI prior to submitting a full proposal. Focus areas include equitable commun...

GrantWatch ID#: 133552

Grants to USA, Canada, and International Nonprofit and For-Profit Entrepreneurial Enterprises ...

Deadline: Ongoing

Grants to USA, Canada, and International nonprofit and for-profit entrepreneurial enterprises for initiatives that address important social issues at the national or global level. Funding is intended to support efforts that aim to improve the lives of individuals throu...

GrantWatch ID#: 161348

Grants to USA, India, and South Africa Nonprofit and For-Profit Social Enterprises to Benefit ...

Deadline: Ongoing

Grants to USA, India, and South Africa nonprofit and for-profit social enterprises for initiatives to benefit children and families living in urban poverty. Areas of focus include education, health, and family economic stability. Funding is intended for proposals that ...

GrantWatch ID#: 162173

Grants to USA, Canada, and International For-Profits and Canada Nonprofits to Collaborate wi...

Deadline: Ongoing

Grants to USA, Canada, and International for-profit organizations and Canada nonprofit organizations to collaborate with universities for research projects in any sector. Applicants must consult staff before applying. The purpose of this program is to solve research ch...

GrantWatch ID#: 162825

Opportunity for USA Veterans with Disabilities to Participate in a Program to Develop Business...

Deadline: Ongoing

Opportunity for USA post-9/11 veterans with service-related disabilities to participate in a program to develop skills and resources related to business management and entrepreneurship. Participants will receive training and mentoring as well as travel and lodging. Pro...

GrantWatch ID#: 164524

Grants to South Dakota Businesses to Support and Enhance Operations and Facilities

Deadline: Ongoing

Grants to South Dakota businesses to support and enhance operations and facilities. Funding may be requested for both new and existing facilities. Primary consideration will be given to projects that would not otherwise occur without the support of this program. Fundin...

GrantWatch ID#: 172168

Grants to USA, Canada, and International Arts Organizations to Promote Canadian Artists Intern...

Deadline: Ongoing

Grants of up to $30,000 to USA, Canada, and International arts organizations for travel expenses aimed at promoting Canadian artistic works and artists internationally. Applicants must be registered in the application portal at least 30 days prior to applying. Funding ...

GrantWatch ID#: 177980

Opportunity for USA Family Members of Eligible Military Veterans to Participate in an Entrepre...

Deadline: Ongoing

Opportunity for USA family members of eligible military veterans to participate in an intensive entrepreneurship education and training program. The program provides self-employment training and mentoring for individuals seeking to start a business. The program, includ...

GrantWatch ID#: 181924

Indemnity Program for USA Livestock Producers to Mitigate Losses Due to Adverse Weather and Ot...

Deadline: Ongoing

Indemnity program to USA livestock producers and owners to mitigate losses exceeding normal mortality due to adverse weather events, disease, and attacks by wild animals. Eligible classes of livestock include, but are not limited to, cattle, poultry, and swine. In add...

GrantWatch ID#: 182186

Emergency Assistance to USA Livestock Producers in Multiple States to Compensate Losses Due to...

Deadline: Ongoing

Emergency assistance to USA and Puerto Rico livestock producers in eligible regions impacted by grazing losses due to weather conditions. Eligible applicants are those located in counties affected by severe or extreme drought. Producers will be compensated for grazing ...

GrantWatch ID#: 182188

Grants to USA Nursery Tree Growers and Orchardists to Mitigate Damages Due to Disease and Natu...

Deadline: Ongoing

Grants to USA nursery tree growers and orchardists to restore and replace qualifying vines, bushes, and trees that have been damaged or lost as a result of disease or natural disaster. Funding may be requested to mitigate losses of commercially produced annual crops. Q...

GrantWatch ID#: 182189

Financial Assistance for USA Producers for Crops Lost Due to Natural Disasters and Adverse Con...

Deadline: Ongoing

Financial assistance to USA agricultural producers to mitigate crop losses due to natural disasters and adverse conditions resulting in low yields, inventory loss, or the prevention of crop planting. Assistance may be requested for commercially produced crops for which...

GrantWatch ID#: 182193

Grants and Cooperative Agreements to USA, Canada, and International Nonprofits, IHEs, For-Prof...

Deadline: Ongoing

Grants and cooperative agreements to USA, Canada, and International nonprofits, IHEs, commercial organizations, individuals, and government agencies to support ocean-related projects, sponsorships, and research. Applicants are advised that required registrations may ta...

GrantWatch ID#: 182597

Grants to USA Qualifying Ag Retailers and Cooperatives in Eligible States to Support Community...

Deadline: Ongoing

Grants of up to $7,500 and grants of up to $10,000 to USA qualifying ag retailers and cooperatives in eligible states to support neighborhood projects. Priority is given to requests that align with farmer well-being and agricultural safety, rural community vitality, an...

GrantWatch ID#: 183059

Opportunity for USA Veteran Business Owners to Participate in a Business Development Program

Deadline: Ongoing

Opportunity for USA veteran business owners to participate in a business development program. The program is intended to assist veterans with successful reintegration into civilian life by providing them with coaching and tools in management, marketing, financial topic...

GrantWatch ID#: 183494

Grants to USA Nonprofits and For-Profits for Continuing Medical Education Programs in the Ar...

Deadline: Ongoing

Grants to USA nonprofit organizations and for-profit continuing medical education providers for education programs for healthcare providers in the area of mental health. Funding is intended for continuing medical education (CME) activities, including live, print, endur...

GrantWatch ID#: 184348