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Grants for South Dakota Nonprofits & 501(c)(3) Organizations

Explore 1,450 active, human-verified grant opportunities tailored for nonprofit organizations, including 501(c)(3) public charities, community organizations, faith-based initiatives, and NGOs operating in South Dakota. Filter funding sources across federal agencies, state programs, private foundations, and corporate giving initiatives spanning 61 grant categories and beyond, updated daily.

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State / Region
Nationwide / International
Grant category
Funding source type

1,450 grants found

Grants to USA, Canada, and International Entities for High-Impact Eye Injury Research

Deadline: 11/12/26 LOI Date: 07/28/26

Grants to USA, Canada, and International nonprofits, for-profits, public entities, intramural organizations, and IHEs for high-impact research projects related to combat-related vision impairments. Applicants must submit a letter of intent and complete the require...

GrantWatch ID#: 215018

Grant to a USA, Canada, or International Nonprofit, For-Profit, Agency, or IHE for Translation...

Deadline: 11/12/26 LOI Date: 07/28/26

Grant to a USA, Canada, or International nonprofit, for-profit, public entity, intramural organization, or IHE for translational research on combat-related eye conditions and injuries. Applicants must submit a letter of intent and complete the required registratio...

GrantWatch ID#: 215019
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Grants to USA Health Professions Schools for Scholarships to Disadvantaged Students

Deadline: 07/28/26

Grants to USA and territories health professions schools to provide scholarships to eligible students. Applicants are advised that required registrations may take several weeks to complete. Funding is intended to increase the number of students from disadvantaged ...

GrantWatch ID#: 217939
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Grants to USA Nonprofits, IHEs, and Agencies, for Engineering and Science Education, Research,...

Deadline: 07/28/26

Grants to USA nonprofit organizations, IHEs, and agencies for engineering and science education, research, and innovation. Applicants are advised that required registrations may take several weeks to complete. Funding is intended for foundational, transdisciplinar...

GrantWatch ID#: 224057

Cooperative Agreements to USA Entities to Develop Resources for Law Enforcement

Deadline: 08/24/26 Conference Date: 07/28/26

Cooperative agreements to USA and territories nonprofit and for-profit organizations, IHEs, and government agencies to develop resources for law enforcement. Applicants are advised that required registrations may take several weeks to complete. Funding is intended...

GrantWatch ID#: 221127
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Grants to USA Nonprofits for Research to Address Inequality for Children and Youth

Deadline: 07/29/26

Grants to USA nonprofit institutions for research to improve the lives of American children and youth up to age 25. Funding is intended to support the effective exploration of policies and activities that address inequality for young people. Priority is given to s...

GrantWatch ID#: 179286
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Grants to USA Nonprofits to Support Research to Benefit Youth

Deadline: 07/29/26

Grants to USA nonprofit organizations for research to benefit youth throughout the country. This program funds investigation into how and what type of research is used by policymakers and others when developing policies and programs affecting young people ages 5-2...

GrantWatch ID#: 184793
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Cooperative Agreement to a USA Entity to Address Long-Term Patient Care Complaints

Deadline: 07/29/26

Cooperative agreement to a USA and territories nonprofit organization, government or tribal agency, community or faith-based organization, hospital, or IHE for training to address long-term facility patient care complaints. Applicants are advised that the required...

GrantWatch ID#: 194801

Grants to USA, Canada, and International Entities for Innovative Lupus Research

Deadline: 08/19/26 LOI Date: 07/29/26

Grants to USA, Canada, and International nonprofit and for-profit organizations, public entities, and IHEs for innovative research projects related to lupus. Applicants must submit a letter of intent and complete the required registrations prior to applying. Fundi...

GrantWatch ID#: 229238

Grants to USA, Canada, and International Entities for Lupus Research

Deadline: 08/19/26 LOI Date: 07/29/26

Grants to USA, Canada, and International nonprofit and for-profit organizations, public entities, and IHEs for research projects related to lupus. Applicants must submit a letter of intent and complete the required registrations prior to applying. Funding is inten...

GrantWatch ID#: 229239

Grants to USA, Canada, and International Entities to Develop Lupus Pilot Studies

Deadline: 08/19/26 LOI Date: 07/29/26

Grants to USA, Canada, and International nonprofit and for-profit organizations, public entities, and IHEs to develop lupus pilot studies. Applicants must submit a letter of intent and complete the required registrations prior to applying. Funding is intended for ...

GrantWatch ID#: 229240

Grants to USA, Canada, and International Entities to Improve Lupus Patient Care

Deadline: 08/19/26 LOI Date: 07/29/26

Grants to USA, Canada, and International nonprofit and for-profit organizations, public entities, and IHEs for research to improve the quality of life of lupus patients. Applicants must submit a letter of intent and complete the required registrations prior to app...

GrantWatch ID#: 229242

Grants to USA State and Native American Governments for Recreational Facilities

Deadline: 11/01/26 Conference Date: 07/29/26

Grants to USA and territories state governments and Native American tribal governments to increase accessibility to recreational activities in underserved and urban communities. Applicants are advised that required registrations may take several months to complete...

GrantWatch ID#: 212095

Grants to USA and Israel Nonprofits to Address Urgent Issues for Girls and Women

Deadline: 09/08/26 Conference Date: 07/29/26

Grants of $20,000 to USA and Israel nonprofit organizations for projects that address urgent issues for girls and women. Funding is intended for projects that improve the lives of girls and women and create positive social change to allow full participation of eve...

GrantWatch ID#: 216267

Opportunity for USA Nonprofits and For-Profits to Create a Digital Military Training Program

Deadline: 11/11/26 Conference Date: 07/29/26 LOI Date: 09/30/26

Opportunity for USA nonprofit and for-profit organizations to compete in a contest to create a fully digital military training program. Applicants are required to submit a preliminary application and complete required registrations prior to a full grant applicatio...

GrantWatch ID#: 230481
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Grants to USA Nonprofit IHEs and Research Institutions to Support Research Fellowships Related...

Deadline: 07/30/26

Grants to USA nonprofit IHEs and research institutions to support research fellowships related to leprosy. Participating fellows are early-career scientists conducting leprosy projects that include scientific studies associated with new clinical trials for leprosy...

GrantWatch ID#: 151729
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Grants to USA and Canada Nonprofits to Promote the Insurance and Risk Management Field

Deadline: 07/30/26

Grants to USA and Canada nonprofit organizations and public and private educational organizations for initiatives to promote the insurance and risk management industry. Funding is intended to support programs that draw new, young talent to the sector and provide o...

GrantWatch ID#: 212391

Grants to USA, Canada, and International Entities for Early-Career Research on MS

Deadline: 08/13/26 LOI Date: 07/30/26

Grants to USA, Canada, and International nonprofit and for-profit organizations, public entities, and IHEs for early-career research projects related to Multiple Sclerosis. Applicants must submit a letter of intent and complete the required registrations prior to ...

GrantWatch ID#: 214914

Grants to USA, Canada, and International Entities for Research on Technologies to Treat Neurol...

Deadline: 09/28/26 LOI Date: 07/30/26

Grants to USA, Canada, and International nonprofit organizations, IHEs, government agencies, for-profits, school districts, and Tribal organizations for research to develop technologies to treat neurological disorders. Applicants are advised that the required regi...

GrantWatch ID#: 217704

Cooperative Agreements to USA Nonprofits, Agencies, Tribes, IHEs, and For-Profits for Translat...

Deadline: 09/28/26 LOI Date: 07/30/26

Cooperative agreements to USA nonprofit organizations, government agencies, tribes, IHEs, and for-profits for translational and clinical brain research. Applicants are advised that the required registrations must be completed prior to applying. Funding is intended...

GrantWatch ID#: 217734

Cooperative Agreements to USA Agencies, For-Profits, IHEs, Tribes, and Nonprofits for Brain Re...

Deadline: 09/28/26 LOI Date: 07/30/26

Cooperative agreements to USA government agencies, for-profits, IHEs, tribes, and nonprofit organizations for brain research. Applicants are advised that the required registrations must be completed prior to applying. Funding is intended for clinical studies for d...

GrantWatch ID#: 217735
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Grants to USA, Canada, and International Organizations for Wildlife Conservation Projects

Deadline: 07/30/26

Grants to USA, Canada, and International organizations for conservation projects and research. Funding is primarily intended for projects related to marine species and parrots, with a focus on endangered species and efforts to conserve biodiversity. Priority is gi...

GrantWatch ID#: 221900
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Grants to USA Investigators to Mitigate the Loss of Federal Research Funding

Deadline: 07/30/26

Grants to USA investigators, IHEs, hospitals, and research institutions to mitigate the loss of federal research funding. Applicants must submit a letter of intent prior to submitting a full application. Funding is intended to support research projects associated ...

GrantWatch ID#: 223698

Grants to USA, Canada, and International Entities for Multiple Sclerosis Clinical Trials

Deadline: 08/13/26 LOI Date: 07/30/26

Grants to USA, Canada, and International for-profit and nonprofit organizations, public entities, and IHEs for clinical trials for multiple sclerosis products, medications, and devices. Applicants must submit a letter of intent and complete required registrations ...

GrantWatch ID#: 229233

Grants to USA, Canada, and International Entities for Multiple Sclerosis Research

Deadline: 08/13/26 LOI Date: 07/30/26

Grants to USA, Canada, and International for-profit and nonprofit organizations, public entities, and IHEs for innovative Multiple Sclerosis research. Applicants must submit a letter of intent and complete required registrations prior to submitting a full proposal...

GrantWatch ID#: 229234

Grants to USA, Canada, and International Entities for High-Impact MS Research

Deadline: 08/13/26 LOI Date: 07/30/26

Grants to USA, Canada, and International for-profit and nonprofit organizations, public entities, and IHEs for high-impact Multiple Sclerosis research. Applicants must submit a letter of intent and complete required registrations prior to submitting a full proposa...

GrantWatch ID#: 229235
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Grants to USA Investigators for Synthetic Plant Biology Research

Deadline: 07/30/26

Grants to USA investigators affiliated with IHEs, research facilities, and research institutes for research related to synthetic plant biology. Funding is intended for projects that apply engineering techniques and principles to advance the understanding of plant ...

GrantWatch ID#: 229996
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Cooperative Agreement to a USA IHE, Nonprofit, or For-Profit for Corrections Staff Training

Deadline: 07/30/26

Cooperative agreement to a USA IHE or nonprofit or for-profit organization for training for corrections staff. Applicants are advised that required registrations may take several weeks to complete. Funding is intended for a training program, resources, and technic...

GrantWatch ID#: 230494

Grants to USA and International Entities for Manufacturing Workforce Training Initiatives

Deadline: 08/25/26 LOI Date: 07/30/26

Grants to USA and International for-profit and nonprofit organizations, schools, and IHEs for workforce training initiatives in eligible regions. Applicants must take an eligibility quiz and register before applying. Funding is intended for addressing training gap...

GrantWatch ID#: 230551

Grant to a USA Nonprofit to Improve Veteran Outcomes

Deadline: 08/25/26 LOI Date: 07/30/26

Grant to a USA nonprofit organization to improve the physical health, mental health, and social connection of veterans and active military members. Applicants must submit a letter of intent prior to submitting a full application. Funding is intended for programs t...

GrantWatch ID#: 230612

Fellowships to USA Postdoctoral Researchers for Research Related to Cardiac Health

Deadline: 08/05/26 Conference Date: 07/30/26

Fellowships to USA postdoctoral researchers affiliated with nonprofit institutions for research related to cardiac health. Funding is intended to enable applicants to develop academic careers in research alongside fulfilling clinical service commitments. Applicant...

GrantWatch ID#: 185142
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Grants to USA Organizations for Programs Serving Armenian-American Youth

Deadline: 07/31/26

Grants to USA organizations to benefit Armenian youth in America. Eligible types of programming include camping, athletic, educational, and cultural activities. The purpose of funding is to promote connection and instill knowledge and appreciation of Armenian cult...

GrantWatch ID#: 142791
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Grants to USA Nonprofits, IHEs, and Tribes for Programming to Improve Workforce Safety

Deadline: 07/31/26

Grants to USA nonprofit organizations, including community and faith-based organizations, labor unions, employer associations, IHEs, and tribal entities to provide educational programs and training related to occupational safety. Applicants are advised that requir...

GrantWatch ID#: 154628
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Grant to a USA Investigator for Research to Assess Physical Therapy Treatment Effectiveness

Deadline: 07/31/26

Grant of $40,000 to a USA emerging investigator affiliated with a qualifying institution or organization for research to assess the clinical effectiveness of interventions in physical therapy within any relevant discipline. Funding is intended to support studies t...

GrantWatch ID#: 157578
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Grants to USA Nonprofits for Projects that Protect Oceans and Improve Water Quality

Deadline: 07/31/26

Grants of up to $25,000 to USA public charitable organizations in eligible watershed regions for projects that preserve and enhance oceanic ecosystems, improve water quality, and protect the environment. Funding is intended for a wide range of projects and activit...

GrantWatch ID#: 171563
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Grant to a USA Investigator for Research on Acute Care Physical Therapy

Deadline: 07/31/26

Grant of $80,000 to a USA investigator affiliated with a qualifying institution or organization for research to enhance knowledge related to acute care physical therapy. Funding is intended to support studies that evaluate the interaction between therapeutic metho...

GrantWatch ID#: 171663
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In-Kind Grants to USA Organizations for Lacrosse Equipment and Instructional Materials

Deadline: 07/31/26

In-kind grants to USA youth-serving organizations for equipment and curriculum materials to enhance participation in the sport of lacrosse. Selected recipients will receive a set of equipment, including lacrosse balls, sticks, cones, and goals, in addition to inst...

GrantWatch ID#: 173934
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Grants to USA Nonprofits to Improve the Lives of At-Risk Military Veterans

Deadline: 07/31/26

Grants to USA nonprofit organizations to improve the lives of injured military veterans and their families. Funding is intended to support a range of services and programs including, but not limited to, therapeutic and recreational activities, career training and ...

GrantWatch ID#: 179275

Grants to USA Nonprofits, Agencies, and Faith-Based Organizations to Benefit Local Communities...

Deadline: 09/15/26 LOI Date: 07/31/26

Grants to USA nonprofit organizations, government agencies, and faith-based organizations for activities that benefit communities across a broad range of focus areas, with an emphasis on geographic locations where family members of the funding source reside. Appli...

GrantWatch ID#: 181847
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Grants to USA Nonprofits to Assist Military Veterans Seeking Careers in Agriculture

Deadline: 07/31/26

Grants to USA nonprofit organizations to provide workforce development opportunities for military veterans in rural areas. Applicants must complete required registrations and contact the funding source prior to submitting a proposal. The purpose of this program is...

GrantWatch ID#: 182599
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Grants to South Dakota Agencies, Tribal Governments, and Local Development Businesses to Impro...

Deadline: 07/31/26

Grants to South Dakota agencies, tribal agencies, and development corporations for improvements to local infrastructure. Before submitting an application, applicants must identify an economic development project and then work with their area planning district to a...

GrantWatch ID#: 184058
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Now

Grants to USA Nonprofits, IHEs, and Tribes to Develop Workplace Safety Training Programs

Deadline: 07/31/26

Grants of up to $95,000 to USA nonprofit organizations, including community and faith-based organizations, labor unions, employer associations, IHEs, and tribal entities to develop educational materials related to occupational safety. Applicants are advised that r...

GrantWatch ID#: 186007
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Grants to USA and Canada Institutions and Organizations for Educational Programs

Deadline: 07/31/26

Grants to USA and Canada institutions and organizations to advance medical education activities for the benefit of researchers and healthcare professionals. Eligible focus areas include multiple sclerosis, lupus, kidney transplantation, and Friedreich ataxia. Fund...

GrantWatch ID#: 193612
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Grant to a USA Emerging Investigator for Physical Therapy Treatment Research

Deadline: 07/31/26

Grant of $40,000 to a USA emerging investigator affiliated with a qualifying institution or organization for research related to physical therapy treatments for patients with musculoskeletal conditions. Funding is intended to support studies that explore clinical ...

GrantWatch ID#: 195466
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Grant to a USA Early-Career Investigator for a High-Risk Physical Therapy Project

Deadline: 07/31/26

Grant of up to $40,000 to a USA early-career investigator affiliated with an organization or institution for an innovative project related to physical therapy treatments. Funding is intended to support high-risk research that has the potential for high impact and ...

GrantWatch ID#: 195467
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Grants to USA and Canada Entities to Advance Patient and Caregiver Education

Deadline: 07/31/26

Grants to USA and Canada organizations and institutions to advance patient education. Funding is intended to support educational activities for patients and caregivers. Eligible proposals have focus areas that include multiple sclerosis, lupus, kidney transplantat...

GrantWatch ID#: 197573
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Grants to USA and Canada Organizations and Institutions for Medical Projects

Deadline: 07/31/26

Grants to USA and Canada organizations and institutions for projects and programs related to multiple sclerosis, lupus, kidney transplantation, and Friedreich ataxia. Funding is intended for activities that drive innovations in science, meet unaddressed patient ne...

GrantWatch ID#: 197585

Grants to USA Nonprofit and Educational Institutions for Scientific Research Projects

Deadline: 09/18/26 LOI Date: 07/31/26

Grants to USA nonprofit and educational institutions for scientific research projects. Applicants must complete required registrations and submit a Letter of Intent prior to submitting a full proposal. Currently funded projects include those in the fields of neuro...

GrantWatch ID#: 200019

Grants to USA Nonprofits to Advance Diversity in the Fields of Entrepreneurship and Investments

Deadline: 10/16/26 LOI Date: 07/31/26

Grants to USA nonprofit organizations to advance diversity in entrepreneurship and investments. Applicants must submit an expression of interest before applying. Funding is intended to empower a more diverse group of investors through five key areas: regional revi...

GrantWatch ID#: 201347
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Grants to USA and International Nonprofits to Benefit Disadvantaged Individuals

Deadline: 07/31/26

Grants to USA and International nonprofit organizations in eligible regions for initiatives that benefit disadvantaged individuals and that provide emergency disaster relief. Funding is intended for a broad range of activities that help individuals become self-suf...

GrantWatch ID#: 203462
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How to Find & Apply for Nonprofit Grants in South Dakota

Securing grant funding starts with identifying opportunities where your mission aligns with the funder's core objectives. Use the GrantWatch directory filters above to narrow your search by category, funding source, and deadline, covering education, healthcare, social justice, capital support, and operating expenses. GrantWatch.com provides subscribers with the most grants for nonprofits and small businesses, including funding for your nonprofit, 501(c)(3), NGO, education, religious or community organization, municipality, small business, individual, or tribal nation. Beyond grant search, GrantWatch is a full grant lifecycle platform, supporting every stage from prospecting through post-award reporting, with the Grant Prospecting Dashboard and Grant Funding Pipeline to track opportunities, GrantWatch Intelligence™ to uncover best-fit funders faster, and the AI Grant Writing Tool to accelerate proposal development.

Frequently Asked Questions

Is there a cost to search or apply for grants on GrantWatch?

A free GrantWatch account includes newsletter updates, access to grant listings, and light use of the Grant Prospecting Dashboard, Grant Funding Pipeline, Claim Your Profile, and AI Grant Writing Tool features. To fully search, filter, and track grants as a serious grant seeker, a MemberPlus+ subscription is required. GrantWatch does not charge a fee to apply for a grant directly with a funding source, and never requires payment in exchange for a guaranteed award.

What types of nonprofit grants are available on GrantWatch?

GrantWatch lists federal, state, local government, corporate, and private foundation grants for nonprofits across 61 categories, including Education, Health and Medical, Housing, Arts and Culture, Youth and At-Risk Youth, and Community Services, along with operating support, capital campaigns, and program expansion funding.

How often is the GrantWatch grant database updated?

GrantWatch's research team human-verifies and updates listings daily, with over a thousand new grant opportunities added each week. Deadlines, eligibility rules, and award amounts are checked regularly to keep the database accurate.

Can newly formed 501(c)(3) organizations apply for these grants?

Eligibility requirements vary by funding source. Review each grant listing's specific criteria to confirm whether your organization qualifies.